WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 462476
CAS#: 1629125-65-0
Description: IDO-IN-4 is an indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor.
MedKoo Cat#: 462476
Name: IDO-IN-4
CAS#: 1629125-65-0
Chemical Formula: C26H35N3O3
Exact Mass: 437.2678
Molecular Weight: 437.584
Elemental Analysis: C, 71.37; H, 8.06; N, 9.60; O, 10.97
Synonym: IDO-IN-4; IDO IN 4; IDO IN-4; IDO-IN 4
IUPAC/Chemical Name: (1R,2S)-2-(4-(diisobutylamino)-3-(3-(p-tolyl)ureido)phenyl)cyclopropane-1-carboxylic acid
InChi Key: VZYCPKLOYXSKAB-FGZHOGPDSA-N
InChi Code: InChI=1S/C26H35N3O3/c1-16(2)14-29(15-17(3)4)24-11-8-19(21-13-22(21)25(30)31)12-23(24)28-26(32)27-20-9-6-18(5)7-10-20/h6-12,16-17,21-22H,13-15H2,1-5H3,(H,30,31)(H2,27,28,32)/t21-,22-/m1/s1
SMILES Code: O=C(NC1=CC=C(C)C=C1)NC2=CC([C@@H](C3)[C@@H]3C(O)=O)=CC=C2N(CC(C)C)CC(C)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 437.584 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Balog, et al. Preparation of cycloalkylaryl amide compounds as indoleamine 2,3-dioxygenase and therapeutic uses thereof. From PCT Int. Appl. (2014), WO 2014150677 A1 20140925.
