WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 462465
Description: ITE is an endogenous aryl hydrocarbon receptor (AhR) agonist.
MedKoo Cat#: 462465
Chemical Formula: C14H10N2O3S
Exact Mass: 286.0412
Molecular Weight: 286.305
Elemental Analysis: C, 58.73; H, 3.52; N, 9.78; O, 16.76; S, 11.20
IUPAC/Chemical Name: methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate
InChi Key: KDDXOGDIPZSCTM-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H10N2O3S/c1-19-14(18)11-7-20-13(16-11)12(17)9-6-15-10-5-3-2-4-8(9)10/h2-7,15H,1H3
SMILES Code: O=C(C1=NC(C(OC)=O)=CS1)C2=CNC3=CC=CC=C32
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 286.305 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Henry, E.C., Bemis, J.C., Henry, O., et al. A potential endogenous ligand for the aryl hydrocarbon receptor has potent agonist activity in vitro and in vivo. Arch. Biochem. Biophys. 450(1), 67-77 (2006).
2: Yoshida, T., Katsuya, K., Oka, T., et al. Effects of AhR ligands on the production of immunoglobulins in purified mouse B cells. Biomed. Res. 33(2), 67-74 (2012).