NVP-CGM097 sulfate

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MedKoo CAT#: 462431

CAS#: 1313367-56-4

Description: NVP-CGM097 sulfate is a potent and selective MDM2 inhibitor.

Price and Availability

Size Price Shipping out time Quantity
5mg USD 460 2 Weeks
10mg USD 735 2 Weeks
50mg USD 2130 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-09-28. Prices are subject to change without notice.

NVP-CGM097 sulfate is in stock.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 462431
Name: NVP-CGM097 sulfate
CAS#: 1313367-56-4
Chemical Formula: 756.2960
Exact Mass: 756.296
Molecular Weight: 757.34
Elemental Analysis: C, 60.27; H, 6.52; Cl, 4.68; N, 7.40; O, 16.90; S, 4.23

Synonym: NVP-CGM097 sulfate; NVP CGM097 sulfate

IUPAC/Chemical Name: (S)-1-(4-chlorophenyl)-7-isopropoxy-6-methoxy-2-(4-(methyl(((1r,4S)-4-(4-methyl-3-oxopiperazin-1-yl)cyclohexyl)methyl)amino)phenyl)-1,4-dihydroisoquinolin-3(2H)-one sulfate


InChi Code: InChI=1S/C38H47ClN4O4.H2O4S/c1-25(2)47-35-22-33-28(20-34(35)46-5)21-36(44)43(38(33)27-8-10-29(39)11-9-27)32-16-14-30(15-17-32)41(4)23-26-6-12-31(13-7-26)42-19-18-40(3)37(45)24-42;1-5(2,3)4/h8-11,14-17,20,22,25-26,31,38H,6-7,12-13,18-19,21,23-24H2,1-5H3;(H2,1,2,3,4)/t26-,31-,38-;/m0./s1

SMILES Code: ClC(C=C1)=CC=C1[C@@H](C2=CC(OC(C)C)=C(OC)C=C2C3)N(C4=CC=C(N(C[C@@H]5CC[C@@H](N6CC(N(C)CC6)=O)CC5)C)C=C4)C3=O.O=S(O)(O)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Holzer P, Masuya K, Furet P, et al. Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors. J Med Chem. 2015;58(16):6348-6358. doi:10.1021/acs.jmedchem.5b00810