Gly-AMC HCl
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MedKoo CAT#: 555820

CAS#: 208459-17-0 (HCl)

Description: Gly-AMC, also known as L-Gly-7-Amino-4-Methylcoumarin, is a probe and chromphore substrate for aminopeptidase. It is useful to make the C-​terminal conjugate of ubiquitin with 7-​amino-​4-​methylcoumarin (Ub-​AMC), which is an important probe for fluorescence-​based anal. of deubiquitinating enzyme (DUB) activity.

Chemical Structure

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Gly-AMC HCl
CAS# 208459-17-0 (HCl)
Product data Instruction

Theoretical Analysis

MedKoo Cat#: 555820
Name: Gly-AMC HCl
CAS#: 208459-17-0 (HCl)
Chemical Formula: C12H13ClN2O3
Exact Mass: 0.00
Molecular Weight: 268.697
Elemental Analysis: C, 53.64; H, 4.88; Cl, 13.19; N, 10.43; O, 17.86

Price and Availability

Size Price Availability Quantity
200mg USD 1250 2 Weeks
500mg USD 1850 2 Weeks
1g USD 2650 2 Weeks
2g USD 4850 2 Weeks
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Related CAS #: 77471-42-2 (free base)   208459-17-0 (HCl)    

Synonym: Gly-AMC HCl; H-Gly-AMC HCl; L-Gly-7-Amino-4-Methylcoumarin; H-Gly-AMC; ; ZINC57339; AK144290; DS-7861; DA-02879; FT-0698956;

IUPAC/Chemical Name: Acetamide, 2-amino-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, monohydrochloride

InChi Key: DGTMMNCLSKYGIF-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H12N2O3.ClH/c1-7-4-12(16)17-10-5-8(2-3-9(7)10)14-11(15)6-13;/h2-5H,6,13H2,1H3,(H,14,15);1H

SMILES Code: O=C(NC1=CC=C(C(O2)=C1)C(C)=CC2=O)CN.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Product Data:
Product Data
Instruction:
View handling instruction
Biological target: Gly-AMC, also known as L-Gly-7-Amino-4-Methylcoumarin, is a probe and chromphore substrate for aminopeptidase.
In vitro activity: TBD
In vivo activity: TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 268.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: TBD
In vitro protocol: TBD
In vivo protocol: TBD

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