WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 462401

CAS#: 1273323-67-3

Description: YLF-466D is a newly developed AMPK activator, which inhibits platelet aggregation.

Chemical Structure

CAS# 1273323-67-3

Theoretical Analysis

MedKoo Cat#: 462401
Name: YLF-466D
CAS#: 1273323-67-3
Chemical Formula: C29H20ClNO3
Exact Mass: 465.1132
Molecular Weight: 465.933
Elemental Analysis: C, 74.76; H, 4.33; Cl, 7.61; N, 3.01; O, 10.30

Price and Availability

Size Price Availability Quantity
5.0mg USD 600.0 2 Weeks
10.0mg USD 890.0 2 Weeks
50.0mg USD 2250.0 2 Weeks
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Synonym: YLF-466D; YLF 466D; YLF466D; C24; C-24; C 24

IUPAC/Chemical Name: (E)-3-((3-((4-chlorophenyl)(phenyl)methylene)-2-oxoindolin-1-yl)methyl)benzoic acid


InChi Code: InChI=1S/C29H20ClNO3/c30-23-15-13-21(14-16-23)26(20-8-2-1-3-9-20)27-24-11-4-5-12-25(24)31(28(27)32)18-19-7-6-10-22(17-19)29(33)34/h1-17H,18H2,(H,33,34)/b27-26+

SMILES Code: O=C(O)C1=CC=CC(CN2C(/C(C3=C2C=CC=C3)=C(C4=CC=C(Cl)C=C4)\C5=CC=CC=C5)=O)=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 465.933 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Liu Y, Park JM, Oh SJ, Chang KH, Lee MY. Antiplatelet effect of a newly developed AMP-activated protein kinase activator YLF-466D. Eur J Pharmacol. 2015;760:81-87. doi:10.1016/j.ejphar.2015.03.084