ICI 207828

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 535054

CAS#: 119778-11-9

Description: ICI 207828 is a bioactive chemical.


Chemical Structure

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ICI 207828
CAS# 119778-11-9

Theoretical Analysis

MedKoo Cat#: 535054
Name: ICI 207828
CAS#: 119778-11-9
Chemical Formula: C24H36BrClN8O3
Exact Mass: 598.1782
Molecular Weight: 599.959
Elemental Analysis: C, 48.05; H, 6.05; Br, 13.32; Cl, 5.91; N, 18.68; O, 8.00

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: ICI 207828; ICI-207828; ICI207828

IUPAC/Chemical Name: Pyrazinecarboxamide, 3,5-diamino-N-(2-((3-((2-(((3-bromo-5-(1,1-dimethylethyl)-2-hydroxyphenyl)methyl)amino)ethyl)amino)-3-oxopropyl)methylamino)ethyl)-6-chloro-

InChi Key: OBRXFUXYWFFYJV-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H36BrClN8O3/c1-24(2,3)15-11-14(19(36)16(25)12-15)13-29-6-7-30-17(35)5-9-34(4)10-8-31-23(37)18-21(27)33-22(28)20(26)32-18/h11-12,29,36H,5-10,13H2,1-4H3,(H,30,35)(H,31,37)(H4,27,28,33)

SMILES Code: ClC1=C(N)N=C(N)C(C(NCCN(CCC(NCCNCC2=CC(C(C)(C)C)=CC(Br)=C2O)=O)C)=O)=N1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 599.959 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Kau ST, Howe BB, Johnston PA, Li JH, Halterman TJ, Zuzack JS, Leszczynska K, Yochim CL, Schwartz JA, Giles RE. Renal and antihypertensive effects of a novel eukalemic diuretic, ICI 207,828. J Pharmacol Exp Ther. 1992 Feb;260(2):450-7. PMID: 1738094.

2: Johnston PA, Kau ST. Evaluation of the renal site of action of a novel, eukalemic diuretic, ICI 207,828. J Pharmacol Exp Ther. 1992 Feb;260(2):458-62. PMID: 1738095.