WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 535047
Description: WY 45727 is a bioactive chemical.
MedKoo Cat#: 535047
Name: WY 45727
Chemical Formula: C16H20N2O3S3
Exact Mass: 384.0636
Molecular Weight: 384.527
Elemental Analysis: C, 49.98; H, 5.24; N, 7.29; O, 12.48; S, 25.01
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: WY 45727; WY-45727; WY45727
IUPAC/Chemical Name: Thieno(3,4-b)thiophen-3-amine, N-(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)-, 1,1-dioxide
InChi Key: XWWRTZCTNGSLNN-UHFFFAOYSA-N
InChi Code: InChI=1S/C16H20N2O3S3/c1-18(2)7-12-3-4-13(21-12)8-22-6-5-17-15-11-24(19,20)16-10-23-9-14(15)16/h3-4,9-11,17H,5-8H2,1-2H3
SMILES Code: CN(CC1=CC=C(CSCCNC2=CS(C3=CSC=C32)(=O)=O)O1)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 384.527 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Nielsen ST. Characterization of the H2 receptor antagonist and gastric acid antisecretory properties of Wy-45,727. J Pharmacol Exp Ther. 1987 Aug;242(2):607-13. PMID: 2886646.
2: MacAllister CG, Sangiah S, Mauromoustakos A. Effect of a histamine H2 type receptor antagonist (WY 45, 727) on the healing of gastric ulcers in ponies. J Vet Intern Med. 1992 Sep-Oct;6(5):271-5. doi: 10.1111/j.1939-1676.1992.tb00351.x. PMID: 1359134.
3: Merki HS, Kaufmann D, Kempf M, Mappes A, Heim J, Roehmel J, Walt RP. Effect of Wy-45,727 on 24 h intragastric acidity in twenty normal volunteers. Br J Clin Pharmacol. 1989 Feb;27(2):135-8. doi: 10.1111/j.1365-2125.1989.tb05343.x. PMID: 2565728; PMCID: PMC1379772.
4: Palumbo GJ, Nielsen ST. The effect of secretagogue selection on potency determinations for gastric acid antisecretory agents. Methods Find Exp Clin Pharmacol. 1988 Mar;10(3):151-5. PMID: 2898575.