WY 45727

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 535047

CAS#: 94662-50-7

Description: WY 45727 is a bioactive chemical.

Chemical Structure

WY 45727
CAS# 94662-50-7

Theoretical Analysis

MedKoo Cat#: 535047
Name: WY 45727
CAS#: 94662-50-7
Chemical Formula: C16H20N2O3S3
Exact Mass: 384.0636
Molecular Weight: 384.527
Elemental Analysis: C, 49.98; H, 5.24; N, 7.29; O, 12.48; S, 25.01

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: WY 45727; WY-45727; WY45727

IUPAC/Chemical Name: Thieno(3,4-b)thiophen-3-amine, N-(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)-, 1,1-dioxide


InChi Code: InChI=1S/C16H20N2O3S3/c1-18(2)7-12-3-4-13(21-12)8-22-6-5-17-15-11-24(19,20)16-10-23-9-14(15)16/h3-4,9-11,17H,5-8H2,1-2H3


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 384.527 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Nielsen ST. Characterization of the H2 receptor antagonist and gastric acid antisecretory properties of Wy-45,727. J Pharmacol Exp Ther. 1987 Aug;242(2):607-13. PMID: 2886646.

2: MacAllister CG, Sangiah S, Mauromoustakos A. Effect of a histamine H2 type receptor antagonist (WY 45, 727) on the healing of gastric ulcers in ponies. J Vet Intern Med. 1992 Sep-Oct;6(5):271-5. doi: 10.1111/j.1939-1676.1992.tb00351.x. PMID: 1359134.

3: Merki HS, Kaufmann D, Kempf M, Mappes A, Heim J, Roehmel J, Walt RP. Effect of Wy-45,727 on 24 h intragastric acidity in twenty normal volunteers. Br J Clin Pharmacol. 1989 Feb;27(2):135-8. doi: 10.1111/j.1365-2125.1989.tb05343.x. PMID: 2565728; PMCID: PMC1379772.

4: Palumbo GJ, Nielsen ST. The effect of secretagogue selection on potency determinations for gastric acid antisecretory agents. Methods Find Exp Clin Pharmacol. 1988 Mar;10(3):151-5. PMID: 2898575.