WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 462342

CAS#: 1895050-66-4

Description: 6RK73 is a covalent irreversible and specific UCHL1 inhibitor. It specifically inhibits UCHL1 activity in breast cancer.

Chemical Structure

CAS# 1895050-66-4

Theoretical Analysis

MedKoo Cat#: 462342
Name: 6RK73
CAS#: 1895050-66-4
Chemical Formula: C13H17N5O2S
Exact Mass: 307.1103
Molecular Weight: 307.372
Elemental Analysis: C, 50.80; H, 5.58; N, 22.79; O, 10.41; S, 10.43

Price and Availability

Size Price Availability Quantity
5.0mg USD 560.0 2 Weeks
10.0mg USD 940.0 2 Weeks
50.0mg USD 2250.0 2 Weeks
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Synonym: 6RK73; 6 RK73; 6-RK73

IUPAC/Chemical Name: (S)-1-cyano-N-(5-morpholinothiazol-2-yl)pyrrolidine-3-carboxamide


InChi Code: InChI=1S/C13H17N5O2S/c14-9-17-2-1-10(8-17)12(19)16-13-15-7-11(21-13)18-3-5-20-6-4-18/h7,10H,1-6,8H2,(H,15,16,19)/t10-/m0/s1


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 307.372 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Liu S, González-Prieto R, Zhang M, et al. Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis. Clin Cancer Res. 2020;26(6):1460-1473. doi:10.1158/1078-0432.CCR-19-1373


5.0mg / USD 560.0