WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 534989
Description: WY 27587 is a bioactive chemical.
MedKoo Cat#: 534989
Name: WY 27587
Chemical Formula: C23H23FN4O2
Exact Mass: 406.1805
Molecular Weight: 406.4614
Elemental Analysis: C, 67.97; H, 5.70; F, 4.67; N, 13.78; O, 7.87
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: WY 27587; WY-27587; WY27587
IUPAC/Chemical Name: 3-Pyridinecarboxamide, N-(((1-((6-fluoro-2-naphthalenyl)methyl)-4-piperidinyl)amino)carbonyl)-
InChi Key: YYWKMPCKXDNMTJ-UHFFFAOYSA-N
InChi Code: InChI=1S/C23H23FN4O2/c24-20-6-5-17-12-16(3-4-18(17)13-20)15-28-10-7-21(8-11-28)26-23(30)27-22(29)19-2-1-9-25-14-19/h1-6,9,12-14,21H,7-8,10-11,15H2,(H2,26,27,29,30)
SMILES Code: O=C(C1=CC=CN=C1)NC(NC2CCN(CC3=CC=C4C=C(F)C=CC4=C3)CC2)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 406.4614 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Billingsley AJ, Brammer NT, Wood MD, Minchin MC. A comparison of the effects of the selective 5-HT uptake inhibitor WY 27587 on 5-HT uptake into platelets and synaptosomes in the rat. Neuropharmacology. 1989 Jan;28(1):33-6. doi: 10.1016/0028-3908(89)90064-6. PMID: 2522598.
2: Bickerdike MJ, Marsden CA, Dourish CT, Fletcher A. The influence of 5-hydroxytryptamine re-uptake blockade on CCK receptor antagonist effects in the rat elevated zero-maze. Eur J Pharmacol. 1994 Dec 27;271(2-3):403-11. doi: 10.1016/0014-2999(94)90800-1. PMID: 7705440.
3: Wardley-Smith B, Hudson S, Doré CJ, Charlett A, Fletcher A, Brammer NT, Minchin MC, Wann KT. Exposure to high pressure may produce the 5-HT behavioral syndrome in rats. Undersea Biomed Res. 1990 Jul;17(4):275-86. PMID: 1697708.