WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 462242
Description: p38 MAPK-IN-2 is an inhibitor of p38 kinase.
MedKoo Cat#: 462242
Name: p38 MAPK-IN-2
Chemical Formula: C20H19ClFN5O2
Exact Mass: 415.1211
Molecular Weight: 415.8534
Elemental Analysis: C, 57.77; H, 4.61; Cl, 8.52; F, 4.57; N, 16.84; O, 7.69
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: p38 MAPK-IN-2; p38 MAPK inhibitor 2
IUPAC/Chemical Name: 1-(4-(5-(4-chloro-2-fluorophenyl)-4-(pyrimidin-4-yl)-1H-pyrazol-3-yl)piperidin-1-yl)-2-hydroxyethan-1-one
InChi Key: IGGNAIYXGIUMQZ-UHFFFAOYSA-N
InChi Code: IGGNAIYXGIUMQZ-UHFFFAOYSA-N
SMILES Code: FC1=CC(Cl)=CC=C1C2=C(C3=NC=NC=C3)C(C4CCN(C(CO)=O)CC4)=NN2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 415.8534 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: CRYSTALLINE FORM OF 2-&lcub 4-‘3-(4-CHLORO-2-FLUOROPHENYL)-4-PYRIMIDIN-4-YL-1H-PYRAZOL-5-YL!PIPERIDIN-1-YL&rcub -2-OXOETHANOL. WO/2005/061486 A1