WAY 161503 hydrochloride
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 574438

CAS#: 276695-22-8

Description: WAY 161503 hydrochloride is a selective 5-HT2C receptor agonist with antidepressant effects.


Chemical Structure

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WAY 161503 hydrochloride
CAS# 276695-22-8

Theoretical Analysis

MedKoo Cat#: 574438
Name: WAY 161503 hydrochloride
CAS#: 276695-22-8
Chemical Formula: C11H12Cl3N3O
Exact Mass: 307.0046
Molecular Weight: 308.59
Elemental Analysis: C, 42.81; H, 3.92; Cl, 34.46; N, 13.62; O, 5.18

Price and Availability

Size Price Availability Quantity
10.0mg USD 335.0 2 Weeks
50.0mg USD 1090.0 2 Weeks
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Synonym: WAY 161503 hydrochloride, WAY 161503 HCl

IUPAC/Chemical Name: 8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride

InChi Key: YPNWSZJDAKOUAW-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H11Cl2N3O.ClH/c12-6-3-8-9(4-7(6)13)16-2-1-14-5-10(16)11(17)15-8;/h3-4,10,14H,1-2,5H2,(H,15,17);1H

SMILES Code: O=C1C(CNCC2)N2C3=C(C=C(Cl)C(Cl)=C3)N1.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 308.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Cryan and Lucki (2000) Antidepressant-like behavioral effects mediated by 5-hydroxytryptamine2C receptors. J.Pharmacol.Exp.Ther. 295 1120 PMID: 11082448

2. Welmaker et al (2000) Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines. Bioorg.Med.Chem.Lett. 10 1991 PMID: 10987434

3. Jensen et al (2013) Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT2A/5-HT2C receptor agonists with pro-cognitive J.Med.Chem. 56 1211 PMID: 23301527