WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 558989
Description: A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.
MedKoo Cat#: 558989
Chemical Formula: C6H8N2O2
Exact Mass: 140.0586
Molecular Weight: 140.142
Elemental Analysis: C, 51.42; H, 5.75; N, 19.99; O, 22.83
Synonym: A6770, A 6770, A-6770
IUPAC/Chemical Name: 1-(5-(hydroxymethyl)-1H-imidazol-2-yl)ethan-1-one
InChi Key: JXDVIQLWMKAZBS-UHFFFAOYSA-N
InChi Code: InChI=1S/C6H8N2O2/c1-4(10)6-7-2-5(3-9)8-6/h2,9H,3H2,1H3,(H,7,8)
SMILES Code: CC(C1=NC=C(CO)N1)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 140.142 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1. Ohtoyo, M., Tamura, M., Machinaga, N., et al. Scintillation proximity assay to detect the changes in cellular dihydrosphingosine 1-phosphate levels. Lipids 51(10), 1207-1216 (2016).