Mycophenolate sodium

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 534858

CAS#: 37415-62-6

Description: Mycophenolate sodium is an immunosuppressant.

Chemical Structure

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Mycophenolate sodium
CAS# 37415-62-6
Instruction

Theoretical Analysis

MedKoo Cat#: 534858
Name: Mycophenolate sodium
CAS#: 37415-62-6
Chemical Formula: C17H19NaO6
Exact Mass: 342.11
Molecular Weight: 342.323
Elemental Analysis: C, 59.65; H, 5.59; Na, 6.72; O, 28.04

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Mycophenolate sodium

IUPAC/Chemical Name: 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, monosodium salt, (4E)-

InChi Key: DOZYTHNHLLSNIK-JOKMOOFLSA-M

InChi Code: InChI=1S/C17H20O6.Na/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3;/h4,20H,5-8H2,1-3H3,(H,18,19);/q;+1/p-1/b9-4+;

SMILES Code: O=C([O-])CC/C(C)=C/CC1=C(O)C2=C(COC2=O)C(C)=C1OC.[Na+]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 342.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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14: Gardiner KM, Tett SE, Staatz CE. Is Conversion from Mycophenolate Mofetil to Enteric-Coated Mycophenolate Sodium Justifiable for Gastrointestinal Quality of Life? Drugs R D. 2018 Dec;18(4):271-282. doi: 10.1007/s40268-018-0254-8. PMID: 30426342; PMCID: PMC6277323.


15: Doukaki S, Platamone A, Alaimo R, Bongiorno MR. Mycophenolate mofetil and enteric-coated mycophenolate sodium in the treatment of pemphigus vulgaris and pemphigus foliaceus. J Dermatolog Treat. 2015 Feb;26(1):67-72. doi: 10.3109/09546634.2014.880395. Epub 2014 Feb 13. PMID: 24521072.


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18: Filler G, Buffo I. Safety considerations with mycophenolate sodium. Expert Opin Drug Saf. 2007 Jul;6(4):445-9. doi: 10.1517/14740338.6.4.445. PMID: 17688388.


19: Cooper M, Salvadori M, Budde K, Oppenheimer F, Sollinger H, Zeier M. Enteric-coated mycophenolate sodium immunosuppression in renal transplant patients: efficacy and dosing. Transplant Rev (Orlando). 2012 Oct;26(4):233-40. doi: 10.1016/j.trre.2012.02.001. Epub 2012 Aug 3. PMID: 22863029.


20: Doycheva D, Zierhut M, Blumenstock G, Sobolewska B, Voykov B, Hohmann J, Spitzer MS, Deuter C. Mycophenolate sodium for the treatment of chronic non- infectious uveitis of childhood. Br J Ophthalmol. 2016 Aug;100(8):1071-5. doi: 10.1136/bjophthalmol-2015-306701. Epub 2015 Nov 13. PMID: 26567021.