WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 534806
CAS#: 93513-59-8
Description: MT81 Mycotoxin is isolated from penicillium nigricans.
MedKoo Cat#: 534806
Name: MT81 Mycotoxin
CAS#: 93513-59-8
Chemical Formula: C22H18O7
Exact Mass: 394.1053
Molecular Weight: 394.379
Elemental Analysis: C, 67.00; H, 4.60; O, 28.40
This product is not in stock, which may be available by custom synthesis.
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Synonym: MT81 Mycotoxin; MT-81 Mycotoxin; MT 81 Mycotoxin
IUPAC/Chemical Name: 9,10-Anthracenedione, 1,5-dihydroxy-3-methyl-8-((2,6,7,7a-tetrahydro-4H-furo(3,2-c)pyran-4-yl)oxy)-
InChi Key: TUSQXSZBOGDCBU-UHFFFAOYSA-N
InChi Code: InChI=1S/C22H18O7/c1-10-8-12-17(14(24)9-10)21(26)19-16(3-2-13(23)18(19)20(12)25)29-22-11-4-6-27-15(11)5-7-28-22/h2-4,8-9,15,22-24H,5-7H2,1H3
SMILES Code: O=C1C2=C(C(O)=CC=C2OC3C4=CCOC4CCO3)C(C5=CC(C)=CC(O)=C15)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 394.379 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Choudhury SM, Gupta M, Majumder UK. Toxicological potential of mycotoxin MT81 and its benzoylated derivative on testicular spermatogenesis and steroidogenesis in mature male Wistar albino rats. Toxicol Mech Methods. 2011 Jun;21(5):426-33. doi: 10.3109/15376516.2011.552535. Epub 2011 Mar 21. PMID: 21417635.
2: Choudhury SM, Gupta M, Majumder UK. Antineoplastic activities of MT81 and its structural analogue in Ehrlich ascites carcinoma-bearing Swiss Albino mice. Oxid Med Cell Longev. 2010 Jan-Feb;3(1):61-70. doi: 10.4161/oxim.3.1.10495. PMID: 20716929; PMCID: PMC2835890.
3: Choudhury S, Rana MP, Chatterjee TK, Mazumder UK, Gupta M. Antimicrobial activities of mycotoxin MT81 and its structural derivatives. Indian J Exp Biol. 1992 Feb;30(2):140-1. PMID: 1521863.
4: Gupta M, Majumdar UK, Ray MR, Mukhopadhayay DK. Inhibition of experimental murine tumors by MT81, a new mycotoxin from Penicillium nigricans. Neoplasma. 1997;44(5):329-33. PMID: 9473795.
5: Mitra M, Mandal AK, Chatterjee TK, Das N. Targeting of mannosylated liposome incorporated benzyl derivative of Penicillium nigricans derived compound MT81 to reticuloendothelial systems for the treatment of visceral leishmaniasis. J Drug Target. 2005 Jun;13(5):285-93. doi: 10.1080/10611860500233306. PMID: 16199372.
6: Liao L, Zhang X, Lou Y, Zhou C, Yuan Q, Gao J. Discovery of Three New Phytotoxins from the Fungus Aspergillus nidulans by Pathway Inactivation. Molecules. 2019 Jan 31;24(3):515. doi: 10.3390/molecules24030515. PMID: 30708999; PMCID: PMC6384659.
7: Majumdar UK, Gupta M, Chowdhury S, Saha AK. Antileishmanial activities of mycotoxin MT 81 and its derivatives. Indian J Exp Biol. 1993 Nov;31(11):888-90. PMID: 8112762.
