UK 370106
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 462157

CAS#: 230961-21-4

Description: UK 370106 is a highly selective MMP-3 and MMP-12 inhibitor.


Price and Availability

Size Price Shipping out time Quantity
10mg USD 430 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-29. Prices are subject to change without notice.

UK 370106, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 462157
Name: UK 370106
CAS#: 230961-21-4
Chemical Formula: C35H44N2O5
Exact Mass: 572.325
Molecular Weight: 572.746
Elemental Analysis: C, 73.40; H, 7.74; N, 4.89; O, 13.97


Synonym: UK 370106; UK-370106; UK370106

IUPAC/Chemical Name: (R)-3-(((S)-1-(((S)-2-methoxy-1-phenylethyl)amino)-3,3-dimethyl-1-oxobutan-2-yl)carbamoyl)-6-(2-methyl-[1,1'-biphenyl]-4-yl)hexanoic acid

InChi Key: NSMABJUGSNPHMN-BHYWQNONSA-N

InChi Code: InChI=1S/C35H44N2O5/c1-24-21-25(19-20-29(24)26-14-8-6-9-15-26)13-12-18-28(22-31(38)39)33(40)37-32(35(2,3)4)34(41)36-30(23-42-5)27-16-10-7-11-17-27/h6-11,14-17,19-21,28,30,32H,12-13,18,22-23H2,1-5H3,(H,36,41)(H,37,40)(H,38,39)/t28-,30-,32-/m1/s1

SMILES Code: O=C([C@H](CCCC1=CC=C(C2=CC=CC=C2)C(C)=C1)CC(O)=O)N[C@@H](C(C)(C)C)C(N[C@H](COC)C3=CC=CC=C3)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Ågren MS, Schnabel R, Christensen LH, Mirastschijski U. Tumor necrosis factor-α-accelerated degradation of type I collagen in human skin is associated with elevated matrix metalloproteinase (MMP)-1 and MMP-3 ex vivo. Eur J Cell Biol. 2015;94(1):12‐21. doi:10.1016/j.ejcb.2014.10.001