WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 462152
CAS#: 2154342-45-5 (HCl)
Description: MUN 42455, also known as Pomalidomide 4'-alkylC3-amine is a cereblon ligand with alkyl linker and terminal amine for onward chemistry. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
MedKoo Cat#: 462152
Name: MUN 42455
CAS#: 2154342-45-5 (HCl)
Chemical Formula: C16H19ClN4O4
Exact Mass: 366.1095
Molecular Weight: 366.802
Elemental Analysis: C, 52.39; H, 5.22; Cl, 9.66; N, 15.27; O, 17.45
Related CAS #: 2093388-20-4 (free base) 2154342-45-5 (HCl)
Synonym: Pomalidomide 4'-alkylC3-amine; MUN 42455; MUN-42455; MUN42455
IUPAC/Chemical Name: 4-[(3-Aminopropyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
InChi Key: MCJLKXXQNIILGB-UHFFFAOYSA-N
InChi Code: InChI=1S/C16H18N4O4.ClH/c17-7-2-8-18-10-4-1-3-9-13(10)16(24)20(15(9)23)11-5-6-12(21)19-14(11)22;/h1,3-4,11,18H,2,5-8,17H2,(H,19,21,22);1H
SMILES Code: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCCN)=O.[H]Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 366.802 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
