WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 534782
CAS#: 1879032-33-3
Description: MRX459 is a bioactive chemical.
MedKoo Cat#: 534782
Name: MRX459
CAS#: 1879032-33-3
Chemical Formula: C18H17F3N4O7
Exact Mass: 458.1049
Molecular Weight: 458.3502
Elemental Analysis: C, 47.17; H, 3.74; F, 12.43; N, 12.22; O, 24.43
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
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Synonym: MRX459; MRX-459; MRX 459
IUPAC/Chemical Name: beta-Alanine, N-(carboxymethyl)-N-(2,3,6-trifluoro-4-((5S)-5-((3-isoxazolylamino)methyl)-2-oxo-3-oxazolidinyl)phenyl)-
InChi Key: RDXYQPOHEAHCST-VIFPVBQESA-N
InChi Code: InChI=1S/C18H17F3N4O7/c19-10-5-11(25-7-9(32-18(25)30)6-22-12-2-4-31-23-12)15(20)16(21)17(10)24(8-14(28)29)3-1-13(26)27/h2,4-5,9H,1,3,6-8H2,(H,22,23)(H,26,27)(H,28,29)/t9-/m0/s1
SMILES Code: O=C(O)CCN(CC(O)=O)C1=C(F)C=C(N2C(O[C@@H](CNC3=NOC=C3)C2)=O)C(F)=C1F
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 458.3502 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Meng J, Zhong D, Li L, Yuan Z, Yuan H, Xie C, Zhou J, Li C, Gordeev MF, Liu J, Chen X. Metabolism of MRX-I, a novel antibacterial oxazolidinone, in humans: the oxidative ring opening of 2,3-Dihydropyridin-4-one catalyzed by non-P450 enzymes. Drug Metab Dispos. 2015 May;43(5):646-59. doi: 10.1124/dmd.114.061747. Epub 2015 Feb 20. PMID: 25710940.
