WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 462150
Description: Yhhu 3792 is a notch signaling pathway activator. It enhances the self-renewal capability of NSCs and is active in vivo.
MedKoo Cat#: 462150
Name: Yhhu 3792
Chemical Formula: C24H25ClN4O2
Exact Mass: 436.1666
Molecular Weight: 436.94
Elemental Analysis: C, 65.97; H, 5.77; Cl, 8.11; N, 12.82; O, 7.32
Synonym: Yhhu 3792
IUPAC/Chemical Name: 5-(3-Methoxyphenoxy)-N2-[4-(1-methylethyl)phenyl]-2,4-quinazolinediamine hydrochloride
InChi Key: WNNJMAWCEOKXEJ-UHFFFAOYSA-N
InChi Code: InChI=1S/C24H24N4O2.ClH/c1-15(2)16-10-12-17(13-11-16)26-24-27-20-8-5-9-21(22(20)23(25)28-24)30-19-7-4-6-18(14-19)29-3;/h4-15H,1-3H3,(H3,25,26,27,28);1H
SMILES Code: NC1=C2C(OC3=CC=CC(OC)=C3)=CC=CC2=NC(NC4=CC=C(C(C)C)C=C4)=N1.[H]Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 436.94 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Lu H, Cheng G, Hong F, Zhang L, Hu Y, Feng L. A Novel 2-Phenylamino-Quinazoline-Based Compound Expands the Neural Stem Cell Pool and Promotes the Hippocampal Neurogenesis and the Cognitive Ability of Adult Mice. Stem Cells. 2018;36(8):1273‐1285. doi:10.1002/stem.2843.