WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 462147
Description: N-(2-Fluorophenethyl)-5-(2-methoxyphenyl)picolinamide is an inhibitor of hypoxia-inducible factor (HIF-1) signaling.
MedKoo Cat#: 462147
Chemical Formula: C21H19FN2O2
Exact Mass: 350.1431
Molecular Weight: 350.3934
Elemental Analysis: C, 71.99; H, 5.47; F, 5.42; N, 8.00; O, 9.13
IUPAC/Chemical Name: N-[2-(2-fluorophenyl)ethyl]-5-(2-methoxyphenyl)-2-pyridinecarboxamide
InChi Key: JZEJSNMITKBPGZ-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H19FN2O2/c1-26-20-9-5-3-7-17(20)16-10-11-19(24-14-16)21(25)23-13-12-15-6-2-4-8-18(15)22/h2-11,14H,12-13H2,1H3,(H,23,25)
SMILES Code: COC1=CC=CC=C1C2=CN=C(C(NCCC3=CC=CC=C3F)=O)C=C2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 350.3934 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Liu, M., Liang, Y., Zhu, Z., et al. Discovery of novel aryl carboxamide derivatives as hypoxia-inducible factor 1α signaling inhibitors with potent activities of anticancer metastasis. J. Med. Chem. 62(20), 9299-9314 (2019).