WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 462114
CAS#: 53199-56-7
Description: SAHO2 is a sulfone form of the methyl donor S-(5'-adenosyl)-L-methionine chloride and is a substrate for radical SAM enzymes.
MedKoo Cat#: 462114
Name: SAHO2
CAS#: 53199-56-7
Chemical Formula: C14H20N6O7S
Exact Mass: 416.1114
Molecular Weight: 416.409
Elemental Analysis: C, 40.38; H, 4.84; N, 20.18; O, 26.89; S, 7.70
Synonym: SAHO2
IUPAC/Chemical Name: 5′-[[(3S)-3-amino-3-carboxypropyl]sulfonyl]-5′-deoxy-adenosine
InChi Key: NUBHDZKYWTVIHP-WFMPWKQPSA-N
InChi Code: InChI=1S/C14H20N6O7S/c15-6(14(23)24)1-2-28(25,26)3-7-9(21)10(22)13(27-7)20-5-19-8-11(16)17-4-18-12(8)20/h4-7,9-10,13,21-22H,1-3,15H2,(H,23,24)(H2,16,17,18)/t6-,7+,9+,10+,13+/m0/s1
SMILES Code: O[C@@H]([C@H]([C@H](N1C=NC2=C(N=CN=C21)N)O3)O)[C@H]3CS(=O)(CC[C@H](N)C(O)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 416.409 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Mandalapu, D., Ji, X., and Zhang, Q. Reductive cleavage of sulfoxide and sulfone by two radical S-adenosyl-L-methionine enzymes. Biochemistry 58(1), 36-39 (2019).
