WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555795

CAS#: 1394371-75-5

Description: DUN71755, also known as nAChR agonist 1, is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR). DUN71755 is reported in WO 2012114285. DUN71755 has CAS#1394371-75-5, no formal name. For the convenience of scientific communication, we named it as DUN71755 (combined from Inchi key plus CAS#) according to Hodoodo Chemical Nomenclature (https://hodoodo.com/hodoodo-chemical-nomenclature).

Price and Availability

Size Price Shipping out time Quantity
200mg USD 2950 2 Weeks
500mg USD 3650 2 Weeks
1g USD 4650 2 Weeks
2g USD 7650 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-01-26. Prices are subject to change without notice.

DUN71755 is in stock.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 555795
Name: DUN71755
CAS#: 1394371-75-5
Chemical Formula: C20H18ClNO3S2
Exact Mass: 419.0417
Molecular Weight: 419.938
Elemental Analysis: C, 57.20; H, 4.32; Cl, 8.44; N, 3.34; O, 11.43; S, 15.27

Synonym: nAChR agonist 1; DUN71755; DUN 71755; DUN-71755;

IUPAC/Chemical Name: 4-(5-(4-chlorophenyl)-4-methyl-2-propionylthiophen-3-yl)benzenesulfonamide


InChi Code: InChI=1S/C20H18ClNO3S2/c1-3-17(23)20-18(13-6-10-16(11-7-13)27(22,24)25)12(2)19(26-20)14-4-8-15(21)9-5-14/h4-11H,3H2,1-2H3,(H2,22,24,25)

SMILES Code: NS(C1=CC=C(C2=C(C(CC)=O)SC(C3=CC=C(Cl)C=C3)=C2C)C=C1)(=O)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


Sinha N, et al.Discovery of Novel, Potent, Brain-Permeable, and Orally Efficacious Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptor [4-(5-(4-Chlorophenyl)-4-methyl-2-propionylthiophen-3-yl)benzenesulfonamide]: Structure-Activity Relationship and Preclinical Characterization. J Med Chem. 2020 Feb 13;63(3):944-960.