Moxaprindine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 534652

CAS#: 53076-26-9

Description: Moxaprindine is a bioactive chemical.

Chemical Structure

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Moxaprindine
CAS# 53076-26-9
Instruction

Theoretical Analysis

MedKoo Cat#: 534652
Name: Moxaprindine
CAS#: 53076-26-9
Chemical Formula: C23H32N2O
Exact Mass: 352.25
Molecular Weight: 352.522
Elemental Analysis: C, 78.36; H, 9.15; N, 7.95; O, 4.54

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Moxaprindine

IUPAC/Chemical Name: 1,3-Propanediamine, N-(2,3-dihydro-1-methoxy-1H-inden-2-yl)-N',N'-diethyl-N-phenyl-

InChi Key: QQGGXAOUSKREAE-UHFFFAOYSA-N

InChi Code: InChI=1S/C23H32N2O/c1-4-24(5-2)16-11-17-25(20-13-7-6-8-14-20)22-18-19-12-9-10-15-21(19)23(22)26-3/h6-10,12-15,22-23H,4-5,11,16-18H2,1-3H3

SMILES Code: CCN(CC)CCCN(C1C(OC)C2=C(C=CC=C2)C1)C3=CC=CC=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 352.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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Reconstitution Calculator

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1: Staessen J, Kesteloot H. Moxaprindine in the acute treatment of ventricular arrhythmias in patients with cardiovascular disease. Eur J Clin Pharmacol. 1981 Feb;19(3):167-72. doi: 10.1007/BF00561943. PMID: 7215413.


2: Teirlynck O, Belpaire FM, Andreasen F. Binding of aprindine and moxaprindine to human serum, alpha 1-acid glycoprotein and serum of healthy and diseased humans. Eur J Clin Pharmacol. 1982;21(5):427-31. doi: 10.1007/BF00542331. PMID: 7075647.


3: de Suray JM, Lavis A, Breekpot F. Pharmacokinetic study of aprindine and moxaprindine in dogs. Int J Clin Pharmacol Ther Toxicol. 1981 May;19(5):209-15. PMID: 7251236.


4: Kesteloot H, van de Werf F, Marchandise B, Sluyts R. Influence of moxaprindine treatment on ventricular arrhythmias occurring during maximal exercise stress testing. Acta Cardiol. 1979;34(5):301-9. PMID: 317204.


5: Waleffe A, Guillaume D, Mary-Rabine L, Kulbertus H. The efficacy of intravenous moxaprindine on ventricular ectopic activity. Acta Cardiol. 1980;35(4):257-68. PMID: 6971032.


6: Stryckmans PA, Ronge-Collard E, Delforge A, Lambert M, Suciu S. Effect of 2 anti-arrhythmic drugs aprindine and moxaprindine on the replication capacity of murine and human haemopoietic cells. Scand J Haematol. 1982 Oct;29(4):331-7. doi: 10.1111/j.1600-0609.1982.tb00603.x. PMID: 7178839.


7: Waleffe A, Mary-Rabine L, Kulbertus HE. Study of moxaprindine with programmed electrical stimulation of the heart in patients with reentrant tachyarrhythmias. Am J Cardiol. 1980 Mar;45(3):640-7. doi: 10.1016/s0002-9149(80)80017-8. PMID: 7355761.