7-Aminoactinomycin D

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 461989

CAS#: 7240-37-1

Description: 7-Aminoactinomycin D is a fluorescent DNA stain.

Chemical Structure

7-Aminoactinomycin D
CAS# 7240-37-1

Theoretical Analysis

MedKoo Cat#: 461989
Name: 7-Aminoactinomycin D
CAS#: 7240-37-1
Chemical Formula: C62H87N13O16
Exact Mass: 1269.6394
Molecular Weight: 1270.453
Elemental Analysis: C, 58.62; H, 6.90; N, 14.33; O, 20.15

Price and Availability

Size Price Availability Quantity
1.0mg USD 325.0 2 Weeks
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Synonym: 7-Aminoactinomycin D; 7-amino-AMD; FLU 402; NSC 239759

IUPAC/Chemical Name: 2,7-Diamino-N1,N9-bis(6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxohexadecahydro-1H-pyrrolo[2,1-i][1]oxa[4,7,10,13]tetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide


InChi Code: InChI=1S/C62H87N13O16/c1-26(2)42-59(85)74-21-17-19-36(74)57(83)70(13)24-38(76)72(15)48(28(5)6)61(87)89-32(11)44(55(81)66-42)68-53(79)34-23-35(63)30(9)51-46(34)65-47-40(41(64)50(78)31(10)52(47)91-51)54(80)69-45-33(12)90-62(88)49(29(7)8)73(16)39(77)25-71(14)58(84)37-20-18-22-75(37)60(86)43(27(3)4)67-56(45)82/h23,26-29,32-33,36-37,42-45,48-49H,17-22,24-25,63-64H2,1-16H3,(H,66,81)(H,67,82)(H,68,79)(H,69,80)

SMILES Code: O=C(C1=C(N)C(C(C)=C2OC3=C(N=C21)C(C(NC4C(NC(C(C)C)C(N5C(CCC5)C(N(C)CC(N(C)C(C(C)C)C(OC4C)=O)=O)=O)=O)=O)=O)=CC(N)=C3C)=O)NC6C(NC(C(C)C)C(N7C(CCC7)C(N(C)CC(N(C)C(C(C)C)C(OC6C)=O)=O)=O)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 1270.453 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Zelenin AV, Poletaev AI, Stepanova NG, Barsky VE, Kolesnikov VA, Nikitin SM, Zhuze AL, Gnutchev NV. 7-Amino-actinomycin D as a specific fluorophore for DNA content analysis by laser flow cytometry. Cytometry. 1984 Jul;5(4):348-54. PubMed PMID: 6468175.

2: Schmid I, Krall WJ, Uittenbogaart CH, Braun J, Giorgi JV. Dead cell discrimination with 7-amino-actinomycin D in combination with dual color immunofluorescence in single laser flow cytometry. Cytometry. 1992;13(2):204-8. PubMed PMID: 1547670.