Sulphamoprine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 461963

CAS#: 155-91-9

Description: Sulphamoprine is a class of sulfonamides which is highly active against dihydropteroate synthase form Toxoplasma gondii, Pneumocystis carinii, and Mycobacterium avium. Sulphamoprine, when given in the diet at levels from 0.025% upwards to pregnant rats and mice, produced abnormalities of eruption of the incisor teeth and of the skull of the offspring. Rabbits are not susceptible to this teratogenic action.


Chemical Structure

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Sulphamoprine
CAS# 155-91-9

Theoretical Analysis

MedKoo Cat#: 461963
Name: Sulphamoprine
CAS#: 155-91-9
Chemical Formula: C12H144N4OS
Exact Mass: 310.07
Molecular Weight: 310.328
Elemental Analysis: C, 46.45; H, 4.55; N, 18.05; O, 20.62; S, 10.33

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Sulphamoprine; ICI 3435; ICI3435; ICI-3435; NSC 8560; NSC-8560; NSC8560;

IUPAC/Chemical Name: Benzenesulfonamide, 4-amino-N-(4,6-dimethoxy-2-pyrimidinyl)-

InChi Key: RMSFTZDTJHYIFE-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H14N4O4S/c1-19-10-7-11(20-2)15-12(14-10)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)

SMILES Code: O=S(C1=CC=C(N)C=C1)(NC2=NC(OC)=CC(OC)=N2)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 310.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: PAGET GE, THORPE E. A TERATOGENIC EFFECT OF A SULPHONAMIDE IN EXPERIMENTAL ANIMALS. Br J Pharmacol Chemother. 1964 Oct;23:305-12. PubMed PMID: 14228132; PubMed Central PMCID: PMC1704094.