NS-3-008 HCl

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555784

CAS#: 1172854-54-4 (HCl)

Description: NS-3-008 is an orally active transcriptional inhibitor of G0/G1 switch 2 (G0s2). NS-3-008 can be used for chronic kidney disease. NS-3-008 inhibited the transcription of G0s2 with a half-maximal inhibitory concentration (IC50) of 2.25 μM. Moreover, treatment of wild-type 5/6Nx mice with NS-3-008 (5 mg/kg, P.O.) resulted in decreased levels of G0s2 and Ccl2 mRNA in the kidneys.

Price and Availability

Size Price Shipping out time Quantity
50mg USD 450 2 Weeks
100mg USD 750 2 Weeks
200mg USD 1250 2 Weeks
500mg USD 1950 2 Weeks
1g USD 2950 2 Weeks
2g USD 5450 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-01-20. Prices are subject to change without notice.

NS-3-008 HCl is in stock.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 555784
Name: NS-3-008 HCl
CAS#: 1172854-54-4 (HCl)
Chemical Formula: C14H24ClN3
Exact Mass:
Molecular Weight: 269.817
Elemental Analysis: C, 62.32; H, 8.97; Cl, 13.14; N, 15.57

Related CAS #: 1172854-54-4 (free base)   1172854-54-4 (HCl)    

Synonym: NS-3-008 HCl; NS-3-008 hydrochloride; NS-3-008; NS 3-008; NS3-008; NS-3008; NS 3008; NS3008;

IUPAC/Chemical Name: 1-benzyl-3-hexylguanidine hydrochloride


InChi Code: InChI=1S/C14H23N3.ClH/c1-2-3-4-8-11-16-14(15)17-12-13-9-6-5-7-10-13;/h5-7,9-10H,2-4,8,11-12H2,1H3,(H3,15,16,17);1H


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Additional Information

Chronic kidney disease (CKD) is a global health problem, and novel therapies to treat CKD are urgently needed. Chronic renal inflammation in CKD was ameliorated by clock mutation. G0s2 was important for the anti-inflammatory effects of clock mutation.