WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 555755
CAS#: 374703-78-3
Description: PKG drug G1 is an activator of protein kinase GIα (PKGIα).
MedKoo Cat#: 555755
Name: PKG Drug G1
CAS#: 374703-78-3
Chemical Formula: C13H11N3OS
Exact Mass: 257.0623
Molecular Weight: 257.311
Elemental Analysis: C, 60.68; H, 4.31; N, 16.33; O, 6.22; S, 12.46
Synonym: PKG Drug G1
IUPAC/Chemical Name: 5-[(2-methyl-1H-indol-3-yl)methylene]-2-thioxo-4-imidazolidinone
InChi Key: SNLLEQAPNVMOOT-WDZFZDKYSA-N
InChi Code: InChI=1S/C13H11N3OS/c1-7-9(6-11-12(17)16-13(18)15-11)8-4-2-3-5-10(8)14-7/h2-6,14H,1H3,(H2,15,16,17,18)/b11-6-
SMILES Code: O=C(/C(N1)=C/C2=C(C)NC3=C2C=CC=C3)NC1=S
1. Burgoyne, J.R., Prysyazhna, O., Richards, D.A., et al. Proof of principle for a novel class of antihypertensives that target the oxidative activation of PKG Iα (protein kinase G Iα). Hypertension 70(3), 577-586 (2017).