WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 555730
Description: QUN88071 is a water soluble Near-Infrared Fluorescent Sensor for in Vivo Imaging. QUN88071 is soluble in pure PBS and newborn calf serum (without addition of any co-organic solvent) with a solubility of at least 2 mM in PBS and 3 mM in newborn calf serum. The unique optical properties of the new type of fluorescent dyes can be exploited as a useful strategy for development of NIR fluorescent sensors.QUN88071 has CAS#1392488-07-1, was first reported in J Am Chem Soc. 2012;134(32):13510–13523 (Compound 1h), and had no convenient name. For the convenience of scientific communication, we named it as QUN88071 (generated by Inchi key plus CAS#) according to Hodoodo Chemical Nomenclature (https://hodoodo.com/hodoodo-chemical-nomenclature).
MedKoo Cat#: 555730
Chemical Formula: C26H25NO8S2
Exact Mass: 543.1022
Molecular Weight: 543.605
Elemental Analysis: C, 57.45; H, 4.64; N, 2.58; O, 23.55; S, 11.80
Synonym: QUN88071; QUN-88071; QUN 88071;
IUPAC/Chemical Name: (E)-6-hydroxy-5-sulfo-4-(2-(1,3,3-trimethyl-3H-indol-1-ium-2-yl)vinyl)-2,3-dihydro-1H-xanthene-7-sulfonate
InChi Key: QPJLDQIEJYZMPZ-UHFFFAOYSA-N
InChi Code: InChI=1S/C26H25NO8S2/c1-26(2)18-9-4-5-10-19(18)27(3)21(26)12-11-15-7-6-8-16-13-17-14-20(36(29,30)31)22(28)25(37(32,33)34)24(17)35-23(15)16/h4-5,9-14H,6-8H2,1-3H3,(H2,29,30,31,32,33,34)
SMILES Code: O=S(C1=C(O)C(S(=O)([O-])=O)=CC2=C1OC3=C(/C=C/C4=[N+](C)C5=C(C=CC=C5)C4(C)C)CCCC3=C2)(O)=O
Fluorescence imaging is a very powerful technique for localization and dynamic monitoring of biomolecules in living systems. The development of new fluorescent imaging sensors has facilitated the recent significant advances in cell biology and medical diagnostic imaging. Near-infrared (NIR) light (650−900 nm) is advantageous to be employed in biological imaging due to minimum photodamage to biological samples, deep tissue penetration, and minimum interference from background autofluorescence by biomolecules in the living systems.
1. Yuan L, Lin W, Zhao S, et al. A unique approach to development of near-infrared fluorescent sensors for in vivo imaging. J Am Chem Soc. 2012;134(32):13510–13523. doi:10.1021/ja305802v