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QUN97653
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555722

CAS#: 1893397-65-3

Description: QUN97653, also known as TBK1/IKKε-IN-5, is a dual TBK1 and IKKε inhibitor, with IC50 values of 1 nM and 5.6 nM for TBK1 and IKKε, respectively. QUN97653 was first reported in patent WO 2016049211. It has CAS#1893397-65-3 without code name. For the convenience of scientific communication, we temporally name it as QUN97653, which was based on Hodoodo Chemical Nomenclature (https://hodoodo.com/hodoodo-chemical-nomenclature).


Price and Availability

Size Price Shipping out time Quantity
100mg USD 1250 4 weeks
200mg USD 1950 4 weeks
500mg USD 2650 4 weeks
1g USD 3650 4 weeks
2g USD 5650 4 weeks
Inquire bulk and customized quantity
Pricing updated 2021-01-23. Prices are subject to change without notice.

QUN97653 or TBK1/IKKε-IN-5, purity > 98%, is under synthesis, which will be available soon.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 555722
Name: QUN97653
CAS#: 1893397-65-3
Chemical Formula: C28H31N7O3
Exact Mass: 513.2488
Molecular Weight: 513.602
Elemental Analysis: C, 65.48; H, 6.08; N, 19.09; O, 9.35


Synonym: TBK1/IKKε-IN-5; QUN97653; QUN-97653; QUN 97653;

IUPAC/Chemical Name: 5-(4-((4-(4-(oxetan-3-yl)piperazin-1-yl)phenyl)amino)-1,3,5-triazin-2-yl)-2-((tetrahydro-2H-pyran-4-yl)oxy)benzonitrile

InChi Key: QYQFLAQHGHBIFA-UHFFFAOYSA-N

InChi Code: InChI=1S/C28H31N7O3/c29-16-21-15-20(1-6-26(21)38-25-7-13-36-14-8-25)27-30-19-31-28(33-27)32-22-2-4-23(5-3-22)34-9-11-35(12-10-34)24-17-37-18-24/h1-6,15,19,24-25H,7-14,17-18H2,(H,30,31,32,33)

SMILES Code: N#CC1=CC(C2=NC(NC3=CC=C(N4CCN(C5COC5)CC4)C=C3)=NC=N2)=CC=C1OC6CCOCC6


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

PCT Int. Appl. (2016), WO 2016049211 A1 20160331. | Language: English, Database: CAPLUS