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MedKoo CAT#: 533394


Description: UC-514321 is a novel selective TET1-signaling inhibitor, directly bind to the DBD of STAT3/5, showing an enhanced effect in repressing the viability of TET1-high AML (including MONOMAC-6, THP-1, and KASUMI-1) cells, as compared with NSC-370284 and other JAK/STAT inhibitors, e.g. Pacritinib, KW-2449, STAT3/5 inhibitor Stattic, or STAT5 inhibitor SC-355979.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-10-31. Prices are subject to change without notice.

UC-514321 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 533394
Name: UC-514321
Chemical Formula: C27H37NO5
Exact Mass: 455.2672
Molecular Weight: 455.595
Elemental Analysis: C, 71.18; H, 8.19; N, 3.07; O, 17.56

Synonym: UC-514321; UC 514321; UC514321

IUPAC/Chemical Name: 6-((3,5-di-tert-Butyl-4-methoxyphenyl)(morpholino)methyl)benzo[d][1,3]dioxol-5-ol


InChi Code: InChI=1S/C27H37NO5/c1-26(2,3)19-12-17(13-20(25(19)30-7)27(4,5)6)24(28-8-10-31-11-9-28)18-14-22-23(15-21(18)29)33-16-32-22/h12-15,24,29H,8-11,16H2,1-7H3

SMILES Code: OC1=C(C(C2=CC(C(C)(C)C)=C(OC)C(C(C)(C)C)=C2)N3CCOCC3)C=C(OCO4)C4=C1

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: