WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 533374

CAS#: 544467-07-4

Description: 118-D-24 is an inhibitor of HSV-1 replication.

Chemical Structure

CAS# 544467-07-4

Theoretical Analysis

MedKoo Cat#: 533374
Name: 118-D-24
CAS#: 544467-07-4
Chemical Formula: C11H9N3O4
Exact Mass: 247.06
Molecular Weight: 247.210
Elemental Analysis: C, 53.44; H, 3.67; N, 17.00; O, 25.89

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Related CAS #: 544467-07-4    

Synonym: 118-D-24; 118-D 24; 118-D24; 118D-24; 118D 24; 118D24;

IUPAC/Chemical Name: 4-[3-(Azidomethyl)phenyl]-2-hydroxy-4-oxo-2-butenoic acid


InChi Code: InChI=1S/C11H9N3O4/c12-14-13-6-7-2-1-3-8(4-7)9(15)5-10(16)11(17)18/h1-5,16H,6H2,(H,17,18)/b10-5-

SMILES Code: O=C(O)/C(O)=C/C(C1=CC=CC(CN=[N+]=[N-])=C1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 247.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

1: Sanchez AB, Varano GP, de Rozieres CM, Maung R, Catalan IC, Dowling CC, Sejbuk NE, Hoefer MM, Kaul M. Antiretrovirals, Methamphetamine, and HIV-1 Envelope Protein gp120 Compromise Neuronal Energy Homeostasis in Association with Various Degrees of Synaptic and Neuritic Damage. Antimicrob Agents Chemother. 2015 Oct 19;60(1):168-79. doi: 10.1128/AAC.01632-15. PMID: 26482305; PMCID: PMC4704202.

2: Mbemba G, Henry E, Delelis O, Bouger MC, Buckle M, Mouscadet JF, Hazan U, Leh H, Bury-Moné S. Biochemical properties of the xenotropic murine leukemia virus- related virus integrase. Biochimie. 2014 Dec;107 Pt B:300-9. doi: 10.1016/j.biochi.2014.09.019. Epub 2014 Sep 26. PMID: 25260582.

3: Yan Z, Bryant KF, Gregory SM, Angelova M, Dreyfus DH, Zhao XZ, Coen DM, Burke TR Jr, Knipe DM. HIV integrase inhibitors block replication of alpha-, beta-, and gammaherpesviruses. mBio. 2014 Jul 1;5(4):e01318-14. doi: 10.1128/mBio.01318-14. PMID: 24987091; PMCID: PMC4161245.

4: McElrath MJ, Ballweber L, Terker A, Kreger A, Sakchalathorn P, Robinson B, Fialkow M, Lentz G, Hladik F. Ex vivo comparison of microbicide efficacies for preventing HIV-1 genomic integration in intraepithelial vaginal cells. Antimicrob Agents Chemother. 2010 Feb;54(2):763-72. doi: 10.1128/AAC.00891-09. Epub 2009 Nov 30. PMID: 19949052; PMCID: PMC2812173