U 78608

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MedKoo CAT#: 585353

CAS#: 123444-35-9

Description: U 78608 is an iron-chelating monocarbam antibiotic.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-09-28. Prices are subject to change without notice.

U 78608 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 585353
Name: U 78608
CAS#: 123444-35-9
Chemical Formula: C21H22N10O11S2
Exact Mass: 654.0911
Molecular Weight: 654.586
Elemental Analysis: C, 38.53; H, 3.39; N, 21.40; O, 26.89; S, 9.80

Synonym: U 78608; U78608; U-78608

IUPAC/Chemical Name: 2-[(E)-[1-(2-Amino-1,3-thiazol-4-yl)-2-[[(3S)-1-[[3-(5-hydroxy-4-oxo-1H-pyridin-2-yl)-4-methyl-5-oxo-1,2,4-triazol-1-yl]sulfonylcarbamoyl]-2-oxoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid


InChi Code: InChI=1S/C21H22N10O11S2/c1-21(2,17(36)37)42-27-13(10-7-43-18(22)25-10)15(34)24-9-6-30(16(9)35)19(38)28-44(40,41)31-20(39)29(3)14(26-31)8-4-11(32)12(33)5-23-8/h4-5,7,9,33H,6H2,1-3H3,(H2,22,25)(H,23,32)(H,24,34)(H,28,38)(H,36,37)/b27-13+/t9-/m0/s1

SMILES Code: CC(C)(O/N=C(C1=CSC(N)=N1)/C(N[C@@H]2C(N(C(NS(=O)(N3N=C(C4=CC(C(O)=CN4)=O)N(C)C3=O)=O)=O)C2)=O)=O)C(O)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Barbachyn MR, Tuominen TC. Synthesis and structure-activity relationships of monocarbams leading to U-78608. J Antibiot (Tokyo). 1990 Sep;43(9):1199-203. PubMed PMID: 2211385.

2: Zurenko GE, Truesdell SE, Yagi BH, Mourey RJ, Laborde AL. In vitro antibacterial activity and interactions with beta-lactamases and penicillin-binding proteins of the new monocarbam antibiotic U-78608. Antimicrob Agents Chemother. 1990 May;34(5):884-8. PubMed PMID: 2193625; PubMed Central PMCID: PMC171711.

3: Dalga RJ, Lambert WJ. Development of a polymer-based reversed-phase high-performance liquid chromatographic stability indicating assay for U-78 608, an iron complexing monocarbam antibiotic. J Chromatogr. 1989 Aug 30;477(2):427-33. PubMed PMID: 2624661.