MB-0223
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 471037

CAS#: 2247732-89-2

Description: MB-0223 is a novel potent and selective STING agonist.


Chemical Structure

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MB-0223
CAS# 2247732-89-2

Theoretical Analysis

MedKoo Cat#: 471037
Name: MB-0223
CAS#: 2247732-89-2
Chemical Formula: C26H27N5OS
Exact Mass: 457.1936
Molecular Weight: 457.6
Elemental Analysis: C, 68.24; H, 5.95; N, 15.30; O, 3.50; S, 7.01

Price and Availability

Size Price Availability Quantity
10.0mg USD 380.0 2 Weeks
50.0mg USD 1150.0 2 Weeks
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Synonym: MB-0223, MB 0223, MB0223

IUPAC/Chemical Name: 4-Methyl-1-((2-(piperidin-1-yl)thiazol-4-yl)methyl)-N-(4-(pyridin-3-yl)phenyl)-1H-pyrrole-2-carboxamide

InChi Key: SWLKFZCOJAYAMJ-UHFFFAOYSA-N

InChi Code: InChI=1S/C26H27N5OS/c1-19-14-24(25(32)28-22-9-7-20(8-10-22)21-6-5-11-27-15-21)31(16-19)17-23-18-33-26(29-23)30-12-3-2-4-13-30/h5-11,14-16,18H,2-4,12-13,17H2,1H3,(H,28,32)

SMILES Code: O=C(C1=CC(C)=CN1CC2=CSC(N3CCCCC3)=N2)NC4=CC=C(C5=CC=CN=C5)C=C4

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 457.6 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Mallat A. et al.; Discovery and characterization of selective small molecule inhibitors of the mammalian mitochondrial division dynamin, DRP1; Biochem Biophys Res Commun. 2018 May 15;499(3):556-562. doi: 10.1016/j.bbrc.2018.03.189. Epub 2018 Apr 4.

MB-0223

10.0mg / USD 380.0