Nexturastat A-CRBN-12d

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MedKoo CAT#: 533268

CAS#: N/A

Description: Nexturastat A-CRBN-12d is a novel potent HDAC6 degrader with promising antiproliferation activity in multiple myeloma (MM) cells.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-10-22. Prices are subject to change without notice.

Nexturastat A-CRBN-12d is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 533268
Name: Nexturastat A-CRBN-12d
CAS#: N/A
Chemical Formula: C39H43N9O8
Exact Mass: 765.3235
Molecular Weight: 765.828
Elemental Analysis: C, 61.17; H, 5.66; N, 16.46; O, 16.71


Synonym: Nexturastat A-CRBN-12d

IUPAC/Chemical Name: 4-(1-Butyl-3-(4-((5-(4-(((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)methyl)-1H-1,2,3-triazol-1-yl)pentyl)oxy)phenyl)ureido)-N-hydroxybenzamide

InChi Key: RDTHJSBFWHNNFX-UHFFFAOYSA-N

InChi Code: InChI=1S/C39H43N9O8/c1-2-3-21-47(28-14-10-25(11-15-28)35(50)44-55)39(54)41-26-12-16-29(17-13-26)56-22-6-4-5-20-46-24-27(43-45-46)23-40-31-9-7-8-30-34(31)38(53)48(37(30)52)32-18-19-33(49)42-36(32)51/h7-17,24,32,40,55H,2-6,18-23H2,1H3,(H,41,54)(H,44,50)(H,42,49,51)

SMILES Code: O=C(NO)C1=CC=C(N(CCCC)C(NC2=CC=C(OCCCCCN3N=NC(CNC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O)=C3)C=C2)=O)C=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001