WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 574134
CAS#: NONE
Description: Oleoyl-D-lysine sodium is an inhibitor of glycine transporter 2a (GlyT2a). It selectively inhibits GlyT2a over GlyT1b and reduces allodynia in a nerve ligation rat model of neuropathic pain.
MedKoo Cat#: 574134
Name: Oleoyl-D-lysine sodium
CAS#: NONE
Chemical Formula: C24H45N2NaO3
Exact Mass: 432.3328
Molecular Weight: 432.62
Elemental Analysis: C, 66.63; H, 10.48; N, 6.48; Na, 5.31; O, 11.09
Synonym: Oleoyl-D-lysine sodium
IUPAC/Chemical Name: N2-[(9Z)-1-oxo-9-octadecen-1-yl]-D-lysine, monosodium salt
InChi Key: OWBHGNNUDAIRSI-KVVVOXFISA-N
InChi Code: InChI=1S/C24H46N2O3.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-23(27)26-22(24(28)29)19-17-18-21-25;/h9-10,22H,2-8,11-21,25H2,1H3,(H,26,27)(H,28,29);/b10-9-;
SMILES Code: O=C(N[C@H](CCCCN)C(O)=O)CCCCCCC/C=C\CCCCCCCC.[Na]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 432.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1. Mostyn, S.N., Rawling, T., Mohammadi, S., et al. Development of an N-acyl amino acid that selectively inhibits the glycine transporter 2 to produce analgesia in a rat model of chronic pain. J. Med. Chem. 62(5), 2466-2484 (2019).
