U 72745G

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MedKoo CAT#: 585310

CAS#: 378-61-0

Description: U 72745G is an angiogenesis factor antagonist.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-09-23. Prices are subject to change without notice.

U 72745G is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 585310
Name: U 72745G
CAS#: 378-61-0
Chemical Formula: C22H29FO4
Exact Mass: 376.205
Molecular Weight: 376.4684
Elemental Analysis: C, 70.19; H, 7.76; F, 5.05; O, 17.00


Synonym: U 72745G; U-42129; U-72,745G; U-72745G

IUPAC/Chemical Name: Pregna-4,9(11)-diene-3,20-dione, 6-fluoro-17,21-dihydroxy-16-methyl-, (6alpha,16alpha)-

InChi Key: MUEOUHRWNRABSW-XUOSUNSOSA-N

InChi Code: InChI=1S/C22H29FO4/c1-12-8-16-14-10-18(23)17-9-13(25)4-6-20(17,2)15(14)5-7-21(16,3)22(12,27)19(26)11-24/h5,9,12,14,16,18,24,27H,4,6-8,10-11H2,1-3H3/t12-,14-,16+,18+,20-,21+,22+/m1/s1

SMILES Code: C[C@@]12[C@](C(CO)=O)(O)[C@H](C)C[C@@]1([H])[C@]3([H])C[C@H](F)C4=CC(CC[C@]4(C)C3=CC2)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Pepper MS, Vassalli JD, Wilks JW, Schweigerer L, Orci L, Montesano R. Modulation of bovine microvascular endothelial cell proteolytic properties by inhibitors of angiogenesis. J Cell Biochem. 1994 Aug;55(4):419-34. PubMed PMID: 7525617.

2: Li WW, Casey R, Gonzalez EM, Folkman J. Angiostatic steroids potentiated by sulfated cyclodextrins inhibit corneal neovascularization. Invest Ophthalmol Vis Sci. 1991 Oct;32(11):2898-905. PubMed PMID: 1917393.