WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 574098

CAS#: 2131223-69-1

Description: YW1159 is an inhibitor of Wnt signaling.

Chemical Structure

CAS# 2131223-69-1

Theoretical Analysis

MedKoo Cat#: 574098
Name: YW1159
CAS#: 2131223-69-1
Chemical Formula: C19H14FN5O
Exact Mass: 347.1182
Molecular Weight: 347.35
Elemental Analysis: C, 65.70; H, 4.06; F, 5.47; N, 20.16; O, 4.61

Price and Availability

Size Price Availability Quantity
1.0mg USD 230.0 2 Weeks
5.0mg USD 525.0 2 Weeks
10.0mg USD 895.0 2 Weeks
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Synonym: Compound 3d, YW1159, YW 1159, YW-1159

IUPAC/Chemical Name: 1-(2-fluorophenyl)-5-methyl-N-2-quinolinyl-1H-1,2,3-triazole-4-carboxamide


InChi Code: InChI=1S/C19H14FN5O/c1-12-18(23-24-25(12)16-9-5-3-7-14(16)20)19(26)22-17-11-10-13-6-2-4-8-15(13)21-17/h2-11H,1H3,(H,21,22,26)

SMILES Code: O=C(C1=C(C)N(C2=C(F)C=CC=C2)N=N1)NC3=CC=C(C=CC=C4)C4=N3

Appearance: A crystalline solid

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 347.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Xue, F., and Shu, Y. Wnt signaling pathway inhibitors for treatments of disease. WO 2017/151786 Al, (2017).

2. Obianom, O.N., Ai, Y., Li, Y., et al. Triazole-based inhibitors of the Wnt/β-catenin signaling pathway improve glucose and lipid metabolism in diet-induced obese mice. J. Med. Chem. 62(2), 727-741 (2019).


1.0mg / USD 230.0

Additional Information

λmax: 257, 318, 332 nm