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MedKoo CAT#: 574097

CAS#: 10540-29-1 (free base)

Description: Tamoxifen is a selective estrogen receptor modulator (SERM) and antagonist of ER action in breast tissue and breast cancer cells. It is reported to be effective in the treatment of early breast cancer to prevent tumor growth. Importantly, tamoxifen has been reported to act as an ER agonist in bone and blood vessels, helping to minimize osteoporosis and reduce the risk of cardiovascular disease in post-menopausal women. Also, tamoxifen is a partial ER agonist in uterine tissues and is reported to increase the risk of endometrial carcinoma.

Price and Availability

Size Price Shipping out time Quantity
500mg USD 225 2 Weeks
1g USD 375 2 Weeks
5g USD 810 2 Weeks
10g USD 1500 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-07-14. Prices are subject to change without notice.

Tamoxifen, purity > 95%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 574097
Name: Tamoxifen
CAS#: 10540-29-1 (free base)
Chemical Formula: C26H29NO
Exact Mass: 371.2249
Molecular Weight: 371.52
Elemental Analysis: C, 84.06; H, 7.87; N, 3.77; O, 4.31

Related CAS #: 54965-24-1 (citrate)   10540-29-1 (free base)  

Synonym: Tamoxifen;ICI 46474, ICI-46474, ICI46474, NSC 180973, tamoxifen, tamoxifeni citras, Nolvadex, Novaldex

IUPAC/Chemical Name: 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-ethanamine


InChi Code: InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-


Technical Data

A crystalline solid

>95% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Additional Information

λmax: 238, 278 nm


1. Horwitz, K.B., and McGuire, W.L. Nuclear mechanisms of estrogen action. Effects of estradiol and anti-estrogens on estrogen receptors and nuclear receptor processing. The Journal of Biological Chemisty 253(22), 8185-8191 (1978).

2. Clarke, M., Collins, R., Davies, C., et al. Tamoxifen for early breast cancer: An overview of the randomised trials. Lancet 351, 1451-1467 (1998).

3. Tonetti, D.A., and Jordan, V.C. Targeted anti-estrogens to treat and prevent diseases in women. Mol. Med. Today 2(5), 218-223 (1996).

4. Jordan, V.C., and Assikis, V.J. Endometrial carcinoma and tamoxifen: Clearing up a controversy. Clinical Cancer Research 1(5), 467-472 (1995).