N,N-Dipropyldopamine HBr
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MedKoo CAT#: 574083

CAS#: 65273-66-7

Description: N,N-Dipropyldopamine HBr is a dopamine receptor agonist. It decreases dihydrophenylalanine (DOPA) levels in the limbic forebrain and striatum as well as reduces homovanillic acid (HVA) levels. N,N-Dipropyldopamine reduces spontaneous locomotor activity in mice, an effect that can be reversed by the antipsychotic spiroperidol.


Chemical Structure

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N,N-Dipropyldopamine HBr
CAS# 65273-66-7

Theoretical Analysis

MedKoo Cat#: 574083
Name: N,N-Dipropyldopamine HBr
CAS#: 65273-66-7
Chemical Formula: C14H24BrNO2
Exact Mass: 317.10
Molecular Weight: 318.260
Elemental Analysis: C, 52.84; H, 7.60; Br, 25.11; N, 4.40; O, 10.05

Price and Availability

Size Price Availability Quantity
1mg USD 220
5mg USD 470
10mg USD 765
25mg USD 1400
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Synonym: N,N-Dipropyldopamine HBr, N,N-Dipropyldopamine hydrobromide

IUPAC/Chemical Name: 4-[2-(dipropylamino)ethyl]-1,2-benzenediol, monohydrobromide

InChi Key: LMYSNFBROWBKMB-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H23NO2/c1-3-8-15(9-4-2)10-7-12-5-6-13(16)14(17)11-12/h5-6,11,16-17H,3-4,7-10H2,1-2H3

SMILES Code: OC1=C(O)C=CC(CCN(CCC)CCC)=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 318.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Wikström, H., Lindberg, P., Martinson, P., et al. Pivaloyl esters of N,N-dialkylated dopamine congeners. Central dopamine-receptor stimulating activity. J. Med. Chem. 21(9), 864-867 (1978).

2. Feenstra, M.G., Rollema, H., Horn, A.S., et al. Effect of dihydroxy-2-aminotetralin derivatives on dopamine metabolism in the rat striatum. Naunyn Schmiedebergs Arch. Pharmacol. 310(3), 219-225 (1980).

3. Costall, B., Lim, S.K., and Naylor, R.J. Characterisation of the mechanisms by which purported dopamine agonists reduce spontaneous locomotor activity of mice. Eur. J. Pharmacol. 73(2-3), 175-188 (1981).