WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 574080

CAS#: 91809-67-5

Description: 6-TAMRA is a fluorescent dye that has commonly been used for the covalent labeling of oligonucleotides for DNA analysis. It displays excitation/emission maxima of 543/572 nm, respectively. 6-Carboxytetramethylrhodamine has been used in various DNA-protein binding studies, DNA FRET experiments, and as a standard reporter or quencher dye in RT-PCR.

Chemical Structure

CAS# 91809-67-5

Theoretical Analysis

MedKoo Cat#: 574080
Name: 6-TAMRA
CAS#: 91809-67-5
Chemical Formula: C25H22N2O5
Exact Mass: 430.1529
Molecular Weight: 430.46
Elemental Analysis: C, 69.76; H, 5.15; N, 6.51; O, 18.58

Price and Availability

Size Price Availability Quantity
100.0mg USD 305.0 2 Weeks
250.0mg USD 565.0 2 Weeks
500.0mg USD 975.0 2 Weeks
1.0g USD 1800.0 2 Weeks
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Synonym: 6-Carboxytetramethylrhodamine, 6-TAMRA

IUPAC/Chemical Name: 9-(2,5-dicarboxyphenyl)-3,6-bis(dimethylamino)-xanthylium, inner salt


InChi Code: InChI=1S/C25H22N2O5/c1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)20-11-14(24(28)29)5-8-17(20)25(30)31/h5-13H,1-4H3,(H-,28,29,30,31)

SMILES Code: [O-]C(C(C=CC(C(O)=O)=C1)=C1C2=C3C=CC(N(C)C)=CC3=[O+]C4=C2C=CC(N(C)C)=C4)=O

Appearance: Very Dark Green to Black Solid

Purity: >90% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Acetonitrile (Slightly), DMSO (Slightly), Methanol (Very Slightly, Heated)

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 430.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Kvach, M.V., Stepanova, I.A., Prokhorenko, I.A., et al. Practical synthesis of isomerically pure 5- and 6-carboxytetramethylrhodamines, useful dyes for DNA probes. Bioconjug. Chem. 20(8), 1673-1682 (2009).

2. Han, C., Chen, T., and Zu, L. Terbium chelate as donor label in time-resolved fluorescence energy transfer study of DNA hybridization. Chem. Phys. Lett. 500(4-6), 323-326 (2010).


100.0mg / USD 305.0

Additional Information

Emission: 572 nm
Excitation: 543 nm
λmax: 253, 353, 546 nm