WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 533078

CAS#: 2369751-30-2

Description: G150 is a Novel potent and highly selective human cGAS inhibitor for repression of dsDNA-triggered interferon expression ( IC50 of 10.2 nM and 25000 nM for h-cGAS and m-cGAS, respectively).

Chemical Structure

CAS# 2369751-30-2

Theoretical Analysis

MedKoo Cat#: 533078
Name: G150
CAS#: 2369751-30-2
Chemical Formula: C18H16Cl2N4O2
Exact Mass: 390.065
Molecular Weight: 391.252
Elemental Analysis: C, 55.26; H, 4.12; Cl, 18.12; N, 14.32; O, 8.18

Price and Availability

Size Price Availability Quantity
5.0mg USD 330.0 2 Weeks
10.0mg USD 580.0 2 Weeks
25.0mg USD 1150.0 2 Weeks
Bulk inquiry

Synonym: G150; G-150; G 150

IUPAC/Chemical Name: 1-(9-(6-Aminopyridin-3-yl)-6,7-dichloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)-2-hydroxyethan-1-one


InChi Code: InChI=1S/C18H16Cl2N4O2/c19-12-5-10(9-1-2-14(21)22-6-9)16-11-7-24(15(26)8-25)4-3-13(11)23-18(16)17(12)20/h1-2,5-6,23,25H,3-4,7-8H2,(H2,21,22)

SMILES Code: O=C(N(C1)CCC(N2)=C1C3=C2C(Cl)=C(Cl)C=C3C4=CC=C(N)N=C4)CO

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 391.252 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.


5.0mg / USD 330.0