Nordimaprit

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 585224

CAS#: 17124-82-2

Description: Nordimaprit is effective agonist in the inhibition of lymphocyte activation.

Chemical Structure

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Nordimaprit
CAS# 17124-82-2
Instruction

Theoretical Analysis

MedKoo Cat#: 585224
Name: Nordimaprit
CAS#: 17124-82-2
Chemical Formula: C5H13N3S
Exact Mass: 147.08
Molecular Weight: 147.240
Elemental Analysis: C, 40.79; H, 8.90; N, 28.54; S, 21.77

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Nordimaprit; SK&F 91487; Skf-91487

IUPAC/Chemical Name: Carbamimidothioic acid, 2-(dimethylamino)ethyl ester

InChi Key: MUYRPUKYVOXLSN-UHFFFAOYSA-N

InChi Code: InChI=1S/C5H13N3S/c1-8(2)3-4-9-5(6)7/h3-4H2,1-2H3,(H3,6,7)

SMILES Code: NC(SCCN(C)C)=N

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 147.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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14: Fechner GA, Jacobs JJ, Parsons PG. Dimaprit analogues inhibit tyrosinase via a disulphide breakdown product independently of the histamine H2 receptor. Biochem Biophys Res Commun. 1994 Jun 15;201(2):687-93. PubMed PMID: 8003003.

15: Leurs R, Brozius MM, Smit MJ, Bast A, Timmerman H. Effects of histamine H1-, H2- and H3-receptor selective drugs on the mechanical activity of guinea-pig small and large intestine. Br J Pharmacol. 1991 Jan;102(1):179-85. PubMed PMID: 1646056; PubMed Central PMCID: PMC1917885.

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17: Fechner GA, Michel J, Sturm RA, Jacobs JJ, Parsons PG. Reduction of DNA synthesis, pigment synthesis, pigmentation gene mRNA and resistance to UVB in human melanoma cells treated with analogues of a histamine (H2) agonist. Biochem Pharmacol. 1994 Jul 5;48(1):121-30. PubMed PMID: 8043013.

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