WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 585189
Description: Swalpamycin is a macrolide antibiotic.
MedKoo Cat#: 585189
Chemical Formula: C37H56O14
Exact Mass: 724.367
Molecular Weight: 724.841
Elemental Analysis: C, 61.31; H, 7.79; O, 30.90
This product is not in stock, which may be available by custom synthesis.
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IUPAC/Chemical Name: Oxacyclohexadeca-3,11,13-triene-2,10-dione, 15-(((6-deoxy-2,3-di-O-methyl-beta-D-allopyranosyl)oxy)methyl)-6-(((4S,5R,6R,7S,9R)-6-hydroxy-4,9-dimethyl-2-oxo-1,3,8-trioxaspiro(4.5)dec-7-yl)oxy)-5,7,9,16-tetramethyl-, (3E,5S,6S,7S,9R,11E,13E,15R,16R)-
InChi Key: AAUZLHJDJNJJDM-KGNKUWBDSA-N
InChi Code: InChI=1S/C37H56O14/c1-19-14-15-28(39)47-23(5)26(18-45-34-32(44-9)31(43-8)29(40)24(6)48-34)12-10-11-13-27(38)20(2)16-21(3)30(19)50-35-33(41)37(17-22(4)46-35)25(7)49-36(42)51-37/h10-15,19-26,29-35,40-41H,16-18H2,1-9H3/b12-10+,13-11+,15-14+/t19-,20+,21-,22+,23+,24+,25-,26+,29+,30+,31+,32+,33-,34+,35-,37-/m0/s1
SMILES Code: O=C(/C=C/[C@H](C)[C@@H](O[C@H](O[C@H](C)C1)[C@H](O)[C@]21[C@H](C)OC(O2)=O)[C@@H](C)C[C@H]3C)O[C@H](C)[C@@H](CO[C@H]4[C@@H]([C@@H]([C@@H]([C@@H](C)O4)O)OC)OC)/C=C/C=C/C3=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 724.841 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Franco CM, Gandhi JN, Chatterjee S, Ganguli BN. Swalpamycin, a new macrolide antibiotic. I. Taxonomy of the producing organism, fermentation, isolation and biological activity. J Antibiot (Tokyo). 1987 Oct;40(10):1361-7. PubMed PMID: 3680001.
2: Chatterjee S, Reddy GC, Franco CM, Rupp RH, Ganguli BN, Fehlhaber HW, Kogler H. Swalpamycin, a new macrolide antibiotic. II. Structure elucidation. J Antibiot (Tokyo). 1987 Oct;40(10):1368-74. PubMed PMID: 3680002.
3: Wang CX, Ding R, Jiang ST, Tang JS, Hu D, Chen GD, Lin F, Hong K, Yao XS, Gao H. Aldgamycins J-O, 16-Membered Macrolides with a Branched Octose Unit from Streptomycetes sp. and Their Antibacterial Activities. J Nat Prod. 2016 Oct 28;79(10):2446-2454. Epub 2016 Sep 30. PubMed PMID: 27690254.