A 1120

Orders received during 11/25~11/29 will be shipped in 11/30/2020 due to Thanksgiving holiday.

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 558768

CAS#: 1152782-19-8

Description: A 1120 is a retinol-binding protein 4 (RBP4) antagonist (Ki = 8.3 nM) that can reduce serum RBP4 and retinol, and displaces transthyretin (TTR) from RBP4-TTR complexes.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-11-25. Prices are subject to change without notice.

is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 558768
Name: A 1120
CAS#: 1152782-19-8
Chemical Formula: C20H19F3N2O3
Exact Mass: 392.1348
Molecular Weight: 392.3782
Elemental Analysis: C, 61.22; H, 4.88; F, 14.53; N, 7.14; O, 12.23

Synonym: A-1120, A1120, 2-(4-(2-(Trifluoromethyl)phenyl)piperidine-1-carboxamido)benzoic acid

IUPAC/Chemical Name: 2-(4-(2-(Trifluoromethyl)phenyl)piperidine-1-carboxamido)benzoic acid



Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Wilkins T, Agabin E, Varghese J, Talukder A. Gallbladder Dysfunction:
Cholecystitis, Choledocholithiasis, Cholangitis, and Biliary Dyskinesia. Prim
Care. 2017 Dec;44(4):575-597. doi: 10.1016/j.pop.2017.07.002. Epub 2017 Oct 5.
Review. PubMed PMID: 29132521.

2: Xue C, Tian Y, Zhang J, Zhao Y, Zhan J, Fang W, Zhang L. Efficacy of BIBF 1120
or BIBF 1120 plus chemotherapy on nasopharyngeal carcinoma in vitro and in vivo.
Drug Des Devel Ther. 2016 Mar 15;10:1173-80. doi: 10.2147/DDDT.S96634.
eCollection 2016. PubMed PMID: 27042009; PubMed Central PMCID: PMC4801128.

3. Manolescu et al (2009) All-trans retinoic acid lowers serum retinol-binding protein 4 concentrations and increases Ins sensitivity in diabetic mice. J.Nutr. 140 311 PMID: 20032483

4. Motani et al (2009) Identification and characterization of a non-retinoid ligand for retinol-binding protein 4 which lowers serum retinol-binding protein 4 levels in vivo. J.Biol.Chem. 284 7673 PMID: 19147488