WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555646

CAS#: 2239272-16-1

Description: AWZ1066S is a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis. AWZ1066S shows superior efficacy to existing anti-Wolbachia therapies in validated preclinical models of infection and has DMPK characteristics that are compatible with a short therapeutic regimen of 7 days or less. This candidate molecule is well-positioned for onward development and has the potential to make a significant impact on communities affected by filariasis.

Price and Availability

Size Price Shipping out time Quantity
100mg USD 1450 2 Weeks
200mg USD 1950 2 Weeks
500mg USD 2950 2 Weeks
1g USD 3950 2 Weeks
2g USD 7450 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-01-18. Prices are subject to change without notice.

AWZ1066S, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 555646
Name: AWZ1066S
CAS#: 2239272-16-1
Chemical Formula: C19H19F3N6O
Exact Mass: 404.1572
Molecular Weight: 404.3972
Elemental Analysis: C, 56.43; H, 4.74; F, 14.09; N, 20.78; O, 3.96

Related CAS #: 2239272-16-1  

Synonym: AWZ1066S; AWZ-1066S; AWZ 1066S; AWZ106S; AWZ-1066; AWZ 1066;

IUPAC/Chemical Name: (S)-2-(3-methylmorpholino)-N-((2-(trifluoromethyl)pyridin-3-yl)methyl)pyrido[2,3-d]pyrimidin-4-amine


InChi Code: InChI=1S/C19H19F3N6O/c1-12-11-29-9-8-28(12)18-26-16-14(5-3-7-24-16)17(27-18)25-10-13-4-2-6-23-15(13)19(20,21)22/h2-7,12H,8-11H2,1H3,(H,24,25,26,27)/t12-/m0/s1


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Hong WD, Benayoud F, Nixon GL, Ford L, Johnston KL, Clare RH, Cassidy A, Cook
DAN, Siu A, Shiotani M, Webborn PJH, Kavanagh S, Aljayyoussi G, Murphy E, Steven
A, Archer J, Struever D, Frohberger SJ, Ehrens A, Hübner MP, Hoerauf A, Roberts
AP, Hubbard ATM, Tate EW, Serwa RA, Leung SC, Qie L, Berry NG, Gusovsky F,
Hemingway J, Turner JD, Taylor MJ, Ward SA, O'Neill PM. AWZ1066S, a highly
specific anti-Wolbachia drug candidate for a short-course treatment of
filariasis. Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1414-1419. doi:
10.1073/pnas.1816585116. Epub 2019 Jan 7. PubMed PMID: 30617067; PubMed Central
PMCID: PMC6347715.