LAU159
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555642

CAS#: 2055050-87-6

Description: LAU159 is a potent modulator of α6β3γ2 GABAA receptor.

Chemical Structure

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LAU159
CAS# 2055050-87-6
Product data Instruction

Theoretical Analysis

MedKoo Cat#: 555642
Name: LAU159
CAS#: 2055050-87-6
Chemical Formula: C17H12ClN3O2
Exact Mass: 325.06
Molecular Weight: 325.752
Elemental Analysis: C, 62.68; H, 3.71; Cl, 10.88; N, 12.90; O, 9.82

Price and Availability

Size Price Availability Quantity
100mg USD 1250
200mg USD 1850
500mg USD 2450
1g USD 3250
2g USD 5650
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Synonym: LAU159; LAU-159; LAU 159;

IUPAC/Chemical Name: 8-chloro-2,5-dihydro-2-(3-methoxyphenyl)-3H-pyrazolo[4,3-c]quinolin-3-one

InChi Key: WQYIIWQWPXNTAK-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H12ClN3O2/c1-23-12-4-2-3-11(8-12)21-17(22)14-9-19-15-6-5-10(18)7-13(15)16(14)20-21/h2-9,19H,1H3

SMILES Code: O=C1N(C2=CC=CC(OC)=C2)N=C3C1=CNC4=C3C=C(Cl)C=C4

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Product Data:
Product Data
Instruction:
View handling instruction
Biological target: LAU159 is a functionally selective positive modulator of α1β3 GABA(A) receptor with an EC50 of 2.2 μM.
In vitro activity: TBD
In vivo activity: TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 325.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: TBD
In vitro protocol: TBD
In vivo protocol: TBD

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