WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532720

CAS#: 1043110-13-9

Description: E09241 is a novel OPG/RANKL upregulator, increasing OPG expression without affecting RANKL expression, promoting osteoblast differentiation while inhibiting osteoclast differentiation, regulating OPG expression through canonical Wnt/β-catenin signaling.

Chemical Structure

CAS# 1043110-13-9

Theoretical Analysis

MedKoo Cat#: 532720
Name: E09241
CAS#: 1043110-13-9
Chemical Formula: C11H9ClN2O2
Exact Mass: 236.04
Molecular Weight: 236.655
Elemental Analysis: C, 55.83; H, 3.83; Cl, 14.98; N, 11.84; O, 13.52

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Synonym: E09241; E-09241; E 09241;

IUPAC/Chemical Name: 5-Chloro-N-(4-methylpyridin-2-yl)furan-2-carboxamide


InChi Code: InChI=1S/C11H9ClN2O2/c1-7-4-5-13-10(6-7)14-11(15)8-2-3-9(12)16-8/h2-6H,1H3,(H,13,14,15)

SMILES Code: O=C(C1=CC=C(Cl)O1)NC2=NC=CC(C)=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Preparing Stock Solutions

The following data is based on the product molecular weight 236.655000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Han X, Gong S, Li N, Wang X, Liu P, Xu Y, He X, Jiang W, Si S. A Novel Small Molecule Which Increases Osteoprotegerin Expression and Protects Against Ovariectomy-Related Bone Loss in Rats. Front Pharmacol. 2019 Mar 11;10:103. doi: 10.3389/fphar.2019.00103. eCollection 2019. PubMed PMID: 30914947; PubMed Central PMCID: PMC6421503.