WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 585129
Description: S 332 is an adrenergic beta3-agonist that is more potent in increasing the urinary storage volume than clenbuterol and less potent in inhibiting the contractile force of urinary bladder at micturition reflex than clenbuterol.
MedKoo Cat#: 585129
Name: S 332
Chemical Formula: C16H17N3O3S
Exact Mass: 331.0991
Molecular Weight: 331.39
Elemental Analysis: C, 57.99; H, 5.17; N, 12.68; O, 14.48; S, 9.67
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: S 332; GS 332; S332; GS332; S-332; GS-332
IUPAC/Chemical Name: Benzenesulfonamide, 3-methyl-4-(5-oxo-3-phenyl-1-imidazolidinyl)-
InChi Key: HUUHHWPSOFUOEV-UHFFFAOYSA-N
InChi Code: InChI=1S/C16H17N3O3S/c1-12-9-14(23(17,21)22)7-8-15(12)19-11-18(10-16(19)20)13-5-3-2-4-6-13/h2-9H,10-11H2,1H3,(H2,17,21,22)
SMILES Code: O=S(C1=CC=C(N(CN(C2=CC=CC=C2)C3)C3=O)C(C)=C1)(N)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 331.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Iizuka H, Osaka Y, Kondo S, Morita T. Effect of an atypical adrenergic beta3-agonist, GS-332: sodium (2R)-[3-[3-[2-(3-chlorophenyl)-2-hydroxyethylamino]cyclohexyl]phenoxy] acetate, on urinary bladder function in rats. J Smooth Muscle Res. 1998 Aug;34(4):139-49. PubMed PMID: 10102799.
2: Yamanishi T, Yasuda K, Kitahara S, Nakai H, Yoshida K, Iizuka H. Effects of 138-355, a beta3-adrenoceptor selective agonist, on relaxation of the human detrusor muscle in vitro. Neurourol Urodyn. 2006;25(7):815-9. PubMed PMID: 16998863.
3: Morita T, Iizuka H, Iwata T, Kondo S. Function and distribution of beta3-adrenoceptors in rat, rabbit and human urinary bladder and external urethral sphincter. J Smooth Muscle Res. 2000 Feb;36(1):21-32. PubMed PMID: 10830475.
4: Yono M, Yoshida M, Takahashi W, Inadome A, Seshita H, Miyamoto Y, Ueda S. Effects of ovarian hormones on beta-adrenergic receptor-mediated relaxation in the female rabbit bladder. Urol Res. 2000 Jan;28(1):38-45. PubMed PMID: 10732694.