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RP-54745
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555619

CAS#: 135330-08-4

Description: RP-54745 is an Inhibitor of macrophage stimulation and interleukin-1 production. RP 54745 might influence certain cells and cytokines implicated in the regulation of the immune system, the disfunctioning of which can lead to inflammatory disorders or autoimmune pathologies. RP-54745 is a very attractive antirheumatic compound and a potentially effective treatment in pathologies where IL-1 production is exacerbated.


Price and Availability

Size Price Shipping out time Quantity
1g USD 3250 2 Weeks
2g USD 5450 2 Weeks
5g USD 7650 2 Weeks
Inquire bulk and customized quantity
Pricing updated 2020-10-31. Prices are subject to change without notice.

RP-54745, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 555619
Name: RP-54745
CAS#: 135330-08-4
Chemical Formula: C13H12ClNOS2
Exact Mass: 297.0049
Molecular Weight: 297.815
Elemental Analysis: C, 52.43; H, 4.06; Cl, 11.90; N, 4.70; O, 5.37; S, 21.53


Synonym: RP-54745; RP 54745; RP54745;

IUPAC/Chemical Name: 4-Chloro-5-(3,4-dihydro-1-methyl-2(1H)-isoquinolinyl)-3H-1,2-dithiol-3-one

InChi Key: BEJJGVDFQORITE-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H12ClNOS2/c1-8-10-5-3-2-4-9(10)6-7-15(8)12-11(14)13(16)18-17-12/h2-5,8H,6-7H2,1H3

SMILES Code: O=C1SSC(N2C(C)C3=C(C=CC=C3)CC2)=C1Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Folliard F, Bousseau A, Terlain B. RP 54745, a potential antirheumatic
compound. II. In vivo properties in different animal models. Agents Actions. 1992
May;36(1-2):127-35. PubMed PMID: 1414681.

2: Folliard F, Bousseau A, Terlain B. RP 54745, a potential antirheumatic
compound. I. Inhibitor of macrophage stimulation and interleukin-1 production.
Agents Actions. 1992 May;36(1-2):119-26. PubMed PMID: 1414680.