Aminozolamide

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 573904

CAS#: 94641-11-9

Description: Aminozolamide is a carbonic anhydrase inhibitor that may be useful in the treatment of ocular hypertension.

Chemical Structure

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Aminozolamide
CAS# 94641-11-9
Instruction

Theoretical Analysis

MedKoo Cat#: 573904
Name: Aminozolamide
CAS#: 94641-11-9
Chemical Formula: C7H7N3O2S2
Exact Mass: 229.00
Molecular Weight: 229.270
Elemental Analysis: C, 36.67; H, 3.08; N, 18.33; O, 13.96; S, 27.97

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Aminozolamide

IUPAC/Chemical Name: 2-Benzothiazolesulfonamide, 6-amino-

InChi Key: OFSGGVHHSMAUEI-UHFFFAOYSA-N

InChi Code: 1S/C7H7N3O2S2/c8-4-1-2-5-6(3-4)13-7(10-5)14(9,11)12/h1-3H,8H2,(H2,9,11,12)

SMILES Code: s1c2cc(N)ccc2nc1S(=O)(=O)N

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 229.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Lewis RA, Schoenwald RD, Barfknecht CF. Aminozolamide suspension: the role of the vehicle in a topical carbonic anhydrase inhibitor. J Ocul Pharmacol. 1988 Fall;4(3):215-9. PubMed PMID: 3198983.

2: Putnam ML, Schoenwald RD, Duffel MW, Barfknecht CF, Segarra TM, Campbell DA. Ocular disposition of aminozolamide in the rabbit eye. Invest Ophthalmol Vis Sci. 1987 Aug;28(8):1373-82. PubMed PMID: 3610554.

3: Lewis RA, Schoenwald RD, Barfknecht CF, Phelps CD. Aminozolamide gel. A trial of a topical carbonic anhydrase inhibitor in ocular hypertension. Arch Ophthalmol. 1986 Jun;104(6):842-4. PubMed PMID: 3521557.