L-2-Aminosuberic acid

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 573902

CAS#: 4254-88-0

Description: L-2-Aminosuberic acid is a biochemical.

Chemical Structure

L-2-Aminosuberic acid
CAS# 4254-88-0

Theoretical Analysis

MedKoo Cat#: 573902
Name: L-2-Aminosuberic acid
CAS#: 4254-88-0
Chemical Formula: C8H15NO4
Exact Mass: 189.1001
Molecular Weight: 189.211
Elemental Analysis: C, 50.78; H, 7.99; N, 7.40; O, 33.82

Price and Availability

Size Price Availability Quantity
100.0mg USD 260.0 2 Weeks
250.0mg USD 450.0 2 Weeks
1.0g USD 825.0 2 Weeks
5.0g USD 2000.0 2 Weeks
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Synonym: (S)-2-Aminooctanedioic acid, Aminosuberic acid, L-2-Aminosuberic acid

IUPAC/Chemical Name: (S)-2-Aminooctanedioic acid


InChi Code: 1S/C8H15NO4/c9-6(8(12)13)4-2-1-3-5-7(10)11/h6H,1-5,9H2,(H,10,11)(H,12,13)/t6-/m0/s1


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Biological target: L-2-Aminosuberic acid is a biochemical.
In vitro activity: TBD
In vivo activity: TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 189.211 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: TBD
In vitro protocol: TBD
In vivo protocol: TBD

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1: Čolović M, Rousseau E, Zhang Z, Lau J, Zhang C, Kuo HT, Yang H, Schaffer P, François Bénard, Lin KS. Synthesis and evaluation of an (18)F-labeled boramino acid analog of aminosuberic acid for PET imaging of the antiporter system x(C)<sup/>. Bioorg Med Chem Lett. 2018 Dec 1;28(22):3579-3584. doi: 10.1016/j.bmcl.2018.06.014. Epub 2018 Jun 8. PubMed PMID: 30316632.

2: Webster JM, Morton CA, Johnson BF, Yang H, Rishel MJ, Lee BD, Miao Q, Pabba C, Yapp DT, Schaffer P. Functional imaging of oxidative stress with a novel PET imaging agent, 18F-5-fluoro-L-aminosuberic acid. J Nucl Med. 2014 Apr;55(4):657-64. doi: 10.2967/jnumed.113.126664. Epub 2014 Feb 27. PubMed PMID: 24578242; PubMed Central PMCID: PMC4009729.

3: Kahnberg P, Lucke AJ, Glenn MP, Boyle GM, Tyndall JD, Parsons PG, Fairlie DP. Design, synthesis, potency, and cytoselectivity of anticancer agents derived by parallel synthesis from alpha-aminosuberic acid. J Med Chem. 2006 Dec 28;49(26):7611-22. PubMed PMID: 17181145.